Prepare the Beef Mixture:

Preheat oven to 375°F (190°C) and grease a 9×13-inch baking dish.

In a large skillet over medium heat, cook the ground beef and diced onion until beef is browned and onions are soft. Drain excess grease.

Add minced garlic, salt, black pepper, Worcestershire sauce, smoked paprika, mustard powder, and Italian seasoning. Cook for another 2 minutes.

Stir in diced tomatoes and condensed cheddar cheese soup. Mix well and simmer for 5 minutes.

Assemble the Casserole:

5. Add cooked macaroni to the beef mixture and stir to combine.

6. Pour the mixture into the prepared baking dish and spread evenly.

7. Sprinkle shredded cheddar and mozzarella cheese evenly over the top.

Bake and Serve:

8. Bake uncovered for 20-25 minutes, or until the cheese is melted and bubbly.

9. Remove from the oven and let sit for 5 minutes before serving.