Cheeseburger Meatloaf Recipe: A Juicy Twist on a Classic Comfort Food

There’s something incredibly satisfying about biting into a juicy, melty cheeseburger. But what if you could capture all that burger goodness in a cozy, baked meatloaf? Enter the cheeseburger meatloaf recipe — a family-friendly dinner that combines the comforting richness of traditional meatloaf with the cheesy, tangy flavors of a cheeseburger. It’s like two comfort food legends rolled into one irresistible dish.

Whether you’re meal-prepping for the week or planning a laid-back Sunday dinner, this cheeseburger meatloaf recipe is sure to please. It’s easy to make, budget-friendly, and packed with bold, familiar flavors that both kids and adults will love.

In this guide, we’ll walk you through every step of the process: from the ingredients and preparation to expert tips, creative variations, sides that pair beautifully, and storage instructions. You’ll also find answers to the most frequently asked questions about this savory dish.

So, grab your apron and let’s dive into the best cheeseburger meatloaf recipe you’ll ever make — one that deserves a permanent spot in your dinner rotation.

Why You’ll Love This Cheeseburger Meatloaf Recipe

There are dozens of meatloaf recipes out there, but this one stands out — and here’s why:

• Cheesy and flavorful: Shredded cheddar or diced American cheese melts into the beef, creating gooey pockets of deliciousness.
• Easy to prepare: With just 15 minutes of prep, it’s a low-effort recipe with high-impact results.
• Customizable: Want to add bacon, jalapeños, or swap out the cheese? You can make it your own with ease.
• Kid-friendly: The familiar flavors of ketchup, mustard, and pickles give it a burger-like taste that even picky eaters can’t resist.

This cheeseburger meatloaf recipe is essentially comfort food at its finest — bold, beefy, cheesy, and baked to golden perfection.

Ingredients You’ll Need

Let’s take a closer look at the simple, pantry-friendly ingredients that make this cheeseburger meatloaf recipe such a standout.

For the Meatloaf:

• 1½ lbs ground beef (80/20) – This ratio gives you the right balance of moisture and flavor.
• 1 cup shredded cheddar cheese – Or substitute with diced American cheese for a true cheeseburger taste.
• ½ cup breadcrumbs – Use plain or panko for binding and structure.
• 2 large eggs – These help bind everything together.
• ½ cup milk – Adds moisture and softness to the meatloaf.
• ¼ cup ketchup – Gives it that burger flair with a hint of sweetness.
• 2 tbsp yellow mustard – A must for that tangy cheeseburger zing.
• 1 tbsp Worcestershire sauce – Deepens the umami flavor.
• ½ tsp garlic powder + ½ tsp onion powder – Essential seasoning duo.
• Salt and pepper to taste – Always taste and adjust!
• ½ cup finely diced onion – Adds subtle sweetness and texture.
• ¼ cup chopped dill pickles (optional) – For that iconic cheeseburger flavor.

For the Glaze:

• ¼ cup ketchup
• 1 tbsp yellow mustard
• 1 tsp brown sugar (optional) – Adds a slight sweet kick that balances the savory meat.

Step-by-Step Instructions for the Perfect Cheeseburger Meatloaf

Follow these easy steps to make a moist, flavorful, and perfectly cooked cheeseburger meatloaf every time.

1. Preheat Your Oven

Preheat your oven to 375°F (190°C). Line a baking sheet with foil or parchment paper for easy cleanup, or use a greased loaf pan.

2. Make the Meatloaf Mixture

In a large mixing bowl, combine all the meatloaf ingredients: ground beef, shredded cheese, breadcrumbs, eggs, milk, ketchup, mustard, Worcestershire, garlic powder, onion powder, diced onion, pickles (if using), salt, and pepper.

Tip: Mix just until the ingredients are combined. Overmixing can result in a tough meatloaf.

3. Shape the Meatloaf

Form the meat mixture into a loaf shape. You can either place it in a standard loaf pan or shape it freeform-style on a baking sheet.

Tip: If using a loaf pan, the meatloaf may take a little longer to cook because of the thicker center.

4. Prepare and Apply the Glaze

In a small bowl, stir together the ketchup, mustard, and brown sugar. Spread the glaze evenly over the top of the meatloaf.

This sweet and tangy glaze caramelizes slightly during baking, adding flavor and a gorgeous finish.

5. Bake

Bake your meatloaf for 55 to 65 minutes, or until the internal temperature reaches 160°F (71°C).

Tip: Use a meat thermometer for accuracy, especially if your meatloaf is thick.

6. Rest and Slice

Remove the meatloaf from the oven and let it rest for at least 10 minutes before slicing. This helps the juices redistribute and prevents it from falling apart.

Tips for the Best Cheeseburger Meatloaf

To elevate your cheeseburger meatloaf game, keep these helpful tips in mind:

• Don’t overmix – Gently combine the ingredients to avoid a dense loaf.
• Use freshly shredded cheese – It melts better and doesn’t contain anti-caking agents.
• Rest before slicing – Always give it 10 minutes post-bake to firm up.
• Add toppings – Sprinkle extra cheese, bacon bits, or crispy onions on top before serving.

Cheeseburger Meatloaf Variations

Want to put your own spin on this recipe? Here are some fun and flavorful ways to make it your own:

• Bacon Cheeseburger Meatloaf: Add cooked, crumbled bacon to the mixture or layer it on top before baking.
• Spicy Kick: Mix in diced jalapeños or a dash of hot sauce.
• BBQ Glaze: Swap ketchup for BBQ sauce in the glaze for a smoky twist.
• Stuffed Version: Create a cheese-stuffed center by layering cheese in the middle of the meatloaf.
• Low-Carb Option: Use almond flour instead of breadcrumbs and skip the brown sugar in the glaze.

The possibilities are endless with this versatile cheeseburger meatloaf recipe!

What to Serve with Cheeseburger Meatloaf

This hearty dish goes perfectly with classic sides or something fresh and crisp to balance the richness.

Top Side Dish Ideas:

• Creamy mashed potatoes – The ultimate comfort pairing.
• Roasted green beans or asparagus – Adds a pop of green and freshness.
• Crisp garden salad – Try a vinaigrette to cut through the meatiness.
• Macaroni and cheese – For those who love full-on indulgence.
• Grilled corn on the cob – A summer BBQ favorite that works year-round.

How to Store and Reheat Cheeseburger Meatloaf

Refrigerator:

Store leftovers in an airtight container for up to 4 days. Let it cool completely before storing.

Freezer:

Wrap the whole meatloaf or individual slices in foil or plastic wrap, then place in a freezer bag. Freeze for up to 3 months.

To Reheat:

• Oven: Bake at 350°F (175°C) until warmed through.
• Microwave: Heat individual slices in 30-second intervals.
• Skillet: Sear slices in a pan for crispy edges.

FAQs about Cheeseburger Meatloaf Recipe

1. Can I use ground turkey instead of beef?

Yes! Ground turkey works well, though the flavor will be slightly different. Add a bit of oil or extra cheese to keep it moist.

2. How do I know when my meatloaf is done?

Use a meat thermometer. The internal temperature should reach 160°F (71°C) for safe consumption.

3. Can I make this meatloaf ahead of time?

Absolutely. Prepare the mixture and shape it into a loaf up to 24 hours in advance. Cover and refrigerate until ready to bake.

4. What cheese works best in cheeseburger meatloaf?

Cheddar or American cheese are top choices, but pepper jack, mozzarella, or Swiss can be fun substitutions.

5. Can I double the recipe?

Yes — just make two loaves or use a larger pan. Adjust baking time accordingly.

6. Is the glaze necessary?

While optional, the glaze adds a lot of flavor and that signature cheeseburger touch. You can also try a BBQ or spicy ketchup glaze for variety.

Conclusion: A Cheeseburger Meatloaf Recipe Worth Repeating

If you’ve been searching for a dinner that’s easy, delicious, and family-approved, this cheeseburger meatloaf recipe checks every box. It captures the spirit of a juicy cheeseburger, wrapped in the nostalgic hug of classic meatloaf. With melty cheese, tangy glaze, and endless customization options, this dish delivers big flavor with minimal effort.

Whether it’s a weeknight meal, a potluck favorite, or part of your Sunday supper tradition, this cheeseburger meatloaf recipe is one you’ll come back to again and again.

So go ahead — make it tonight, and let the compliments roll in. You’ve just unlocked a new family favorite.

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